Sleep near the station or across the river. Day-ticket the galleries. Chianti is a separate afternoon.
The Duomo complex
Cathedral, dome, baptistery, campanile. Pick the climb you booked. You do not need every interior ticket.
Uffizi and Accademia
Two buildings, two mornings. The Vasari Corridor is a bonus, not a first-trip requirement.
Oltrarno and Ponte Vecchio
Workshops, quieter streets, dinner. The bridge is the link, not the destination.
Chianti, Siena, San Gimignano
A day of hills and wine. Belongs on a 3-night Florence stay or a 14-day Italy trip.